Dear Reader, Imagine a world where every child, regardless of their condition, has access to safe, effective, and child-friendly therapies. This vision has been the driving force behind CVBF since its inception in 2000. Our journey truly gained momentum in 2005 with our first EU funded project, the FP6 “TEDDY Task-force in Europe for [...]
The U.S. Food and Drug Administration (FDA) has reported a significant increase in the number of planned studies to test drugs for pediatric cancers, thanks to the Research Acceleration for Cure and Equity (RACE) for Children Act enacted in 2017. This regulatory change has accelerated the expansion of the pediatric oncology armamentarium, with the [...]
CVBF was among the participants at the European Joint Programme on Rare Diseases (EJP RD) Final Conference, held on 27-28 May 2024 in Bari, Italy. The event brought together experts, professionals, and advocates involved in rare disease efforts from around the world. The two-day conference provided a platform for discussing challenges and advancements related to [...]
Donato Bonifazi, CEO of CVBF and a member of the Board of Directors of the Teddy European Network of Excellence for Paediatric Clinical Research, will participate in upcoming EnprEMA (European Network of Paediatric Research at the European Medicines Agency) meetings and working groups. Teddy is involved in several active and proposed EnprEMA working groups: [...]
CVBF embraces an innovative computational approach to advance research in paediatric rare diseases, involving the creation of virtual patient cohorts and the use of in silico trials. At the two-day conference "Il Ruolo del Farmacologo nell'applicazione delle Metodologie Innovative nella Ricerca Preclinica e Clinica Pediatrica" held on 21-22 March 2024 and hosted by the Società [...]
The OrphaDev4Kids project, focused on advancing medical devices development for rare diseases in children, will officially launch with a kick-off meeting on 19 July 2024 in Bari, Italy. This event brings together the project partners to align on objectives and map out the key activities. Under the moderation of Donato Bonifazi, CEO of CVBF, the [...]
The European Paediatric Translational Research Infrastructure (EPTRI) has exciting news to share about its upcoming Scientific Meeting and legal incorporation as an international non-profit association. EPTRI is pleased to announce its General Assembly and Scientific Meeting will be held on 18-19 July 2024 in Bari, Italy. This two-day event will bring together researchers, industry, [...]
Mark your calendars! The 2024 iCAN Advocacy and Research Summit is scheduled to take place from 15-19 July in Bari, Italy. This event brings together iCAN chapters worldwide for five days focused on paediatric research and healthcare innovation, collaboration, and advocacy. Thanks to the collaboration of the TEDDY Network the iCAN Summit 2024 will see [...]
Recent publications from researchers affiliated with the CVBF consortium underscore our commitment to advancing efforts in paediatric data standardization. The paper by Mariagrazia Felisi, Fedele Bonifazi, Claudia Pansieri, Giorgio Reggiardo, Donato Bonifazi, Adriana Ceci and others mapped out existing data repositories for sharing paediatric clinical trial data. Though promoting transparency, their rapid review found only [...]
Thanks to the collaboration with the TEDDY Network, CVBF has published two new lay summaries explaining the key findings of the DEEP-2 paediatric clinical study in a kid-friendly way. One is tailored for children aged 6-12 years old, while the other targets adolescents aged 12-18. The DEEP-2 study evaluated an oral formulation for treating [...]
