DIVA: Innovative devices for the prevention of recurrent VAginites

DIVA: Innovative devices for the prevention of recurrent VAginites 2018-08-22T08:53:08+00:00

Role of CVBF

Partner

Description

DIVA project intends to develop an innovative treatment specific for recurrent vaginitis with the aim to reduce the use of the antibiotic therapy. In particular, this objective is acquired through the development of:
1. A food enriched with probiotic lactobacilli with antimicrobial activity and dietary fibres;
2. Device / cosmetic with bacteriostatic and fungicidal action derived from plant products;
3. Sanitary towels functionalized with bacteria and fungicidal extracts derived from plant products;
The treatment foresees both the intake of a food based on specific lactobacilli for the modulation of the intestinal microbiota and the use of a product (cosmetic or device medical) for vaginal use based on substances with bacteriostatic and fungicidal action. The versatility and high technology of the instruments that are used for the transformation of the raw material guarantee to operate with production processes ensuring full compliance with environmental sustainability. The CVBF in the project deals with developing the context analysis related to Puglia Region area, with the aim to describe and define both the clinical problem and its incidence as well as the technologies and the alternative treatments available and their costs. In addition, the CVBF will provide support for the clinical trial conduct, with the aim to evaluate the effects of the combination of the double approach (probiotics intestinal and vaginal products) compared to standard therapy in the prevention of recurrent vaginal infections. Moreover, the activities of the CVBF include medical writing, clinical study planning and management, regulatory and ethical activities, pharmacovigilance, data management, monitoring and auditing.

Funds

POR Puglia FESR-FSE 2014-2020 – InnoNetwork

Budget

2,063,215 euro

Contribution

1,496,191 euro

Duration

18 months

Partners

Sergio Fontana SRL, Stella Maris di Garofalo Vanessa, PLUSIMPLE SRL, BIOMERIS SRL SPIN OFF, SANIGEN SPA, Consorzio Per Valutazioni Biologiche e Farmacologiche (CVBF), University of Bari “A. Moro”, Dipartimento di Scienze del Suolo, della Pianta e degli Alimenti (D.I.S.S.P.A.), Dipartimento di Farmacia – Scienze del Farmaco, Dipartimento di Scienze Biomediche e Oncologia Umana (DIMO).